Genetically altered, Pinky was happy-go-lucky, but dim-witted while Brain was seemingly unemotional and very intelligent. One of the recurring segments followed Pinky and Brain, two lab rats at Acme Labs. Every episode would have three segments that focused on any of the dozen or so characters that surrounded the Warner siblings Dot, Yakko, and Wakko. Besides being one of the most successful cartoon series and collecting a cult following after its time on the air, Animaniacs introduced the world to many new and original characters due to its segmented episode structure. RELATED: Looney Tunes: 10 Characters That Time Forgot Pinky and the Brain’s Originsīefore the jump to their own series, Pinky and the Brain were seen on Animaniacs, a children’s animated series that began in 1993. The most obvious and famous cartoon spinoff is The Simpsons, going from small sketches on The Tracey Ullman Show to the longest-running animated series ever (with no plans of stopping anytime soon), but around the same time that The Simpsonswas skyrocketing in the 1990s, another cartoon spinoff series was getting its footing and would soon be labeled as one of the best spinoffs of all time - Pinky and the Brain. There are plenty of overly successful spinoff shows, from Fraiser to the endless Stark Trek series, but only a few successful spinoff series are animated. Not all get to be as successful or beloved as their original source material - Friends spinoff Joey was considered a failure with two seasons, while That 80s Show made the mistake of airing while That 70s Show was still on the air - but some become just as loved or even more memorable than the original show. Spinoffs are a staple of modern television.
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